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Butylone is made up of a methyl substitution at RN, a substitution which happens to be shared with MDEA, ethylone, 4-MEC, and specified other stimulants and entactogens. On top of that, butylone consists of substitutions at R3 and R4 on the phenyl ring with oxygen teams. These oxygen teams are included right into a methylenedioxy ring via a methyle